According to the world health organization who, the odontogenic myxoma is classified as an odontogenic tumor of ectomesenchymal origin. The odontogenic myxoma is a rare entity located in mandible and upper maxilla. In the majority of cases, diagnosis is largely dependent on. It begins with a slow growing tumor but can lead to massive cortical bone expansion and destruction of bone at its later stages, implying its infiltrative behavior. Odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Odontogenic myxoma om is a rare benign tumour originated from odontogenic ectomesenchyme, 1 characterized by local invasion and tendency to reoccur. Peripheral odontogenic myxoma is a rare odontogenic tumor representing an extra osseous counterpart of central odontogenic myxoma. Case report with reconstructive considerations odontogenic myxoma. Odontogenic myxomaa case report and clinicoradiographic study of seven tumors. This report describes a case of odontogenic myxoma producing diffusely dispersed calcified products in a. A large and rapidly expanding odontogenic myxoma of the. Odontogenic myxomaa case report and clinicoradiographic. Third most frequent odontogenic tumor after odontoma and ameloblastoma recurrence rate 25% odontogenic myxoma. The mandibular odontogenic myxoma is a tumor of mesenchymal origin.
Odontogenic myxoma is an uncommon benign mesenchymal odontogenic tumor arising from the dental papilla, follicle, or the periodontal ligament. It is nonencapsulated, arises from odontogenic ectomesenchyme, develops solely in the jaws, and represent a small percentage of odontogenic tumor overall. An irregular soft tissue mass lesion is seen arising from right maxillary bone alveolar process, measuring 6 x 4. Odontogenic myxoma om is a benign but locally aggressive and nonmetastasising neoplasm of the jaws. Odontogenic myxoma of the maxilla a rare case report ramkumar subramaiam, 1 sangeetha narashiman, 2 malathi narasimhan, 3 veda giri, 4 and santhosh kumar 5 1 professor, department of oral and maxillofacial surgery, faculty of dental sciences, sri ramachandra university, ramachandra nagar, porur chennai, tamilnadu, india. Odontogenic myxomas are considered to be a benign odontogenic tumor with locally aggres sive behavior. There is no evidence in the literature in regard to the best treatment approach, in terms of conservative or aggressive surgery, for this type of tumor. Pdf odontogenic myxoma om is a locally aggressive, benign, slowgrowing.
The tumour arose in a 53yearold patient, recurred two times after extended maxillectomy and ultimately caused the patients death by uncontrollable local disease with infiltration of the cranial cavity. An odontogenic myxoma of the maxilla with an aggressive clinical course is presented. Note tooth displaced to the floor of the orbit and the upper premolars distally. There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Odontogenic myxoma is usually asymptomatic and is found incidentally on radiographs, appearing as a soap bubble.
Mar 19, 2012 the odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. Pubmed is a searchable database of medical literature and lists journal articles that discuss odontogenic myxoma. Educational video created by unmc college of dentistry class of 2016 dental students. Odontogenic myxoma is a rare benign but locally aggressive odontogenic tumor.
It is a histologically benign but locally aggressive and prone to tumor recurrence, which determines treatment. Case report an unusual odontogenic myxoma in mandible and submandibular region. Odontogenic myxoma is a benign tumor, mostly located in the mandible. Colman and rinaldo canalis department of oral and maxillofacial surgery and division of otolaryngology, harhorucla medical center, california, usa abstract the odontogenic myxoma is a relatively rare. Epidemiology typically seen in the 2nd to 3rd decades of life slightly earlier than ameloblastomas. Odontogenic myxoma is even rarer in children than in adults. Colman and rinaldo canalis department of oral and maxillofacial surgery and division of otolaryngology, harhorucla medical center, california, usa abstract the odontogenic myxoma is a relatively rare benign tumor occurring in the jaws.
Odontogenic myxoma of the maxilla a rare case report. Conjunctival myxomas are thought to originate in tenons capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface squamous neoplasia ossn, or amelanotic melanoma. Case report an unusual odontogenic myxoma in mandible. This report describes a case of odontogenic myxoma producing diffusely dispersed calcified products in a pattern. This wide variation in incidence may be attributed to the rarity of the lesion. Case report with reconstructive considerations spencer, k. Lo muzio l, nocini p, favia g, procaccini m, mignogna md.
Introduction in 2003, the world health organization who classified odontogenic myxoma om as a benign neoplasm arising from odontogenic ectomesenchyme with or without odontogenic epithelium goldman and thoma were the first to describe om of the jaws in 1947. Ameloblastoma, a type of odontogenic tumor involving ameloblasts. Figure 2 from odontogenic myxomaa case report and clinico. Reported incidence rates of odontogenic myxoma range from 0. Several surgical techniques have been described for the reconstruction of segmental mandibular defects. Case report an unusual odontogenic myxoma in mandible and. Odontogenic myxoma are intraosseous lesions originating in embri onic connective tissue.
Odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. Odontogenic myxoma is a very rare benign tumor that may arise in the maxilla or mandible, but which can be locally aggressive. Diagnosis and management of odontogenic myxoma in a dog. There is no study in the literature that analyses the best standards for om diagnosis and how the treatment modalities may influence the recurrence rates. Benign odontogenic neoplasm characterized by bland, spindled to stellate cells set in myxoid stroma. However, in spite of its mandibular occurrence the present case is invading, and more aggressive which is a rare finding.
Odontogenic myxoma genetic and rare diseases information. The evidence for its odontogenic origin arises from its almost exclusive location in the toothbearing areas of the jaws, its occasional association with missing or unerupted teeth and the presence of. Mandibular reconstruction by fibula free flap and fixed implant supported denture astor jochelson, national diploma. Reconstruction of mandibular defects with bone marrow. We report 2 cases one case is a 33 years patient and the second one is. This paper reports a case of odontogenic myxoma in a child treated with a. Odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones. Department of oral and maxillofacial surgery, faculty of. Odontogenic myxoma radiographically multilocular radiolucencies soapbubbles appearance.
Mar 05, 2012 odontogenic myxoma radiographically multilocular radiolucencies soapbubbles appearance. Free tissue transfer provides many reconstructive options for the head and neck scieeon and is reliable for restoring nearnormal functional recovery. The odontogenic myxoma is generally considered to be a rare neoplasm unique to the jaws. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors 2. Usually odontogenic myxoma is seen in the second and third decades of life having a similar distribution in males and females. Odontogenic myxoma om is a benign, locally invasive and. This report highlights central odontogenic myxoma in a 43yearold male. A large and rapidly expanding odontogenic myxoma of the mandible sajad ahmad buch, subhas g babu, kumuda rao, shruthi rao, renita lorina castelino department of oral medicine and radiology, a b shetty memorial institute of dental sciences, deralakatte, nitte university, mangalore, karnataka, india.
Odontogenic myxoma definition of odontogenic myxoma by. Odontogenic myxoma e561 introduction odontogenic myxoma om is a rare benign tumor that originates from odontogenic ectomesenchyme 1,2. In the majority of cases, diagnosis is largely dependent on the histopathological findings. Odontogenic myxoma om is a locally invasive benign tumour of the. This paper reports a case of odontogenic myxoma in a child treated with. Benign odontogenic lesions are rare entities but are very important due to their locally aggressive nature. Odontogenic myxoma is a rare, benign intraosseous tumor. This disease affects mostly young adults between the second and third decades of life, but can occur at any age. You may need to register to view the medical textbook, but registration is free. It shows locally aggressive behavior and requires surgical removal. Once thought to be an entity confined to the second or third decade of life in terms of onset, odontogenic myxoma of the jaws has been identified to have a higher occurrence rate in the pediatric population 78. It represents approximately 3 6% of all odontogenic tumors. Benign odontogenic myxoid lesion composed of spindled to stellate cells. Tiejun li, lisha sun, and haiyan luo 2006 odontogenic myxoma.
Clinicopathologic analysis of 14 cases of odontogenic. Odontogenic myxoma of the jaws is a rare slow growing. This is a case report of odontogenic myxoma in a 32 year old female patient and the treatment rendered to her. The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. Odontogenic myxoma om is a rare neoplasm, which originates from odontogenic ectomesenchyme. Odontogenic myxoma of the maxilla is less frequent but behaves more aggressively than that of the mandible. Odontogenic myxoma is a rare tumour of the jaw, making both its diagnosis and management challenging.
May 29, 2014 educational video created by unmc college of dentistry class of 2016 dental students. In one large retrospective study, odontogenic myxoma constituted about 3% of 706 odontogenic tumors regezi, 2002. Odontogenic myxoma ddmfr oral and maxillofacial radiology. The lesions can be found in the maxilla and mandible. In comparison with other free flaps, the vascularized free fibular flap vfff supports the lon. It presents local invasiveness and tendency to recurrence. Common treatment options for reconstructing the bone defects are immediate or delayed autologous bone graft or free flap. As a myxoma, this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material. Due to its local aggressiveness, wide surgical excision is mandatory. Comparison of radiographic and mri features of a rootdiverging odontogenic myxoma, with discussion of the differential diagnosis of lesions likely to move roots. This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a case managed. Background odontogenic myxoma om is a benign but locally aggressive and nonmetastasising neoplasm of the jaws.
Odontogenic myxoma om is a benign tumor derived from embryonic mesenchymal elements of a developing tooth including the dental follicle, dental papilla, or periodontal ligament. Odontogenic myxoma is an uncommon tumor of the jaws. A large and rapidly expanding odontogenic myxoma of the mandible. Dental technology department of dental sciences, cape town university of technology, cape town, south africa, 2006 p.
It is commonly seen in gingiva between the 3rd and 4th decades of. Odontogenic myxoma om is a rare entity of slowly growing benign neoplasm of ectomesenchymal origin, comprising of 36% of all odontogenic tumors that. Peripheral odontogenic myxoma pom is extraosseous variant of odontogenic myxomas, occurring solely in the soft tissue covering the tooth bearing portion of jaws. Odontogenic myxoma histologically1 3 2 1myxoma filling marrow spaces. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. They are silent lesions clinically and show myxoid stroma amidst fibrous background.
In the international histological classification of odontogenic tumors, odontogenic myxoma om is defined as a benign odontogenic tumor of mesenchymal origin that is locally invasive and consists of rounded and angular cells lying in. Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Click on the link to view a sample search on this topic. It can occur at any age but most commonly in the second and third decades of life.
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